Near Hillsgrove, the Loyalsock Creek is a large freestone river known for its wild trout. The headwaters of the Loyalsock Creek are above the town of Lopez. The stream flows 50 miles to the confluence with the West Branch of the Susquehanna River. You can expect to find plenty of wild and stocked trout in the deep pools and runs. While wading is the way to go, it can be challenging at times.
The upper section is from the confluence of Pole Bridge Run down to the confluence with the Little Loyalsock Creek near Forksville. This section is stocked and is very scenic, however, the fishing may not be as good as in other sections. Access is provided by SR154.
The lower section is below Forksville down to the West Branch. Access is provided by SR87, but there a limited public access points.
Overall, Loyalsock Creek is the 9th most popular fly fishing river of all 49 fly fishing spots in Pennsylvania.