Near Coburn, the Penns Creek is popular with local fly fishermen for its prolific green drake hatch which is typically in late May through early June.
The upper section of Penns Creek is from the headwaters north of Spring Mills down to Coburn at the Elk Creek confluence. This 7 mile section is pretty gentle and flows through farmlands. You can expect to find plenty of wild brown trout. This section is best during April and May.
The middle section of Penns Creek is from the Elk Creek confluence downstream to the Swift Run Confluence near Poe Paddy Campground. This 7 mile catch-and-release section is a designated All Tackle Trophy Trout area.
The lower section of Penns Creek is from Swift Run downstream to Cherry Run. This 3.9 mile section is designated catch-and-release and has some large brown trout.
The fly fishing on Penns Creek is accessed from SR45.
Overall, Penns Creek is the 19th most popular fly fishing river of all 49 fly fishing spots in Pennsylvania.